The barbiturates are nonselective central nervous program depressants which happen to be largely employed as sedative hypnotics and in addition anticonvulsants in subhypnotic doses. The barbiturates as well as their sodium salts are matter to control underneath the Federal Managed Substances Act (Se

pentobarbital increases toxicity of methoxyflurane by increasing metabolism. Contraindicated. Enhanced metabolism of methoxyflurane to nephrotoxic compounds. pentobarbital will lower the extent or result of buprenorphine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watc